ZRSR2 Antibody, Biotin conjugated

Datasheet

Code	CSB-PA618014LD01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ZRSR2 Polyclonal antibody

Uniprot No.

Q15696

Target Names

ZRSR2

Alternative Names

CCCH type zinc finger antibody; CCCH type zinc finger; RNA binding motif and serine/arginine rich protein 2 antibody; MGC142014 antibody; MGC142040 antibody; Renal carcinoma antigen NY REN 20 antibody; Renal carcinoma antigen NY-REN-20 antibody; RNA-binding motif and serine/arginine rich protein 2 antibody; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related protein 2 antibody; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 antibody; U2(RNU2) small nuclear RNA auxiliary factor 1 like 2 antibody; U2(RNU2) small nuclear RNA auxiliary factor 1-like 2 antibody; U2AF1 RS2 antibody; U2AF1L2 antibody; U2AF1RS2 antibody; U2AF35-related protein antibody; U2AFM_HUMAN antibody; URP antibody; Zinc finger-; CCCH domain-; and RNA-binding motif-containing serine/arginine-rich protein 2 antibody; Zrsr2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 protein (191-372AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Biotin

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3'-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.

Gene References into Functions

We conclude that the common clinical features of patients with an isolated mutation of ZRSR2 are a macrocytic anemia without leukopenia, thrombocytopenia or an increase in marrow blast percentage PMID: 28942350
ZRSR2 has a role in RNA splicing; dysregulated splicing of U12-type introns is a characteristic feature of ZRSR2 mutations in myelodysplastic syndrome PMID: 25586593
Data show that through recognition of a common splicing element, Urp facilitates distinct steps of U2- and U12-type intron splicing. PMID: 21041408

Subcellular Location

Nucleus.

Tissue Specificity

Widely expressed.

Database Links

HGNC: 23019

OMIM: 300028

KEGG: hsa:8233

STRING: 9606.ENSP00000303015

UniGene: Hs.171909

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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